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Single-Minded Homolog 2 (SIM2) (Middle Region) Peptid

SIM2 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5518205

Kurzübersicht für Single-Minded Homolog 2 (SIM2) (Middle Region) Peptid (ABIN5518205)

Target

SIM2 (Single-Minded Homolog 2 (SIM2))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    SWRTALSTSQ ETRKLVKPKN TKMKTKLRTN PYPPQQYSSF QMDKLECGQL
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SIM2 (Single-Minded Homolog 2 (SIM2))

    Hintergrund

    This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

    Alias Symbols: SIM, bHLHe15, HMC13F06, HMC29C01

    Protein Size: 167

    Gen-ID

    6493

    NCBI Accession

    NM_005069, NP_005060

    UniProt

    Q14190
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